Growing protein crystals can be a major challenge. Now, new crystallographic tools and methods can help us solve structures from nano-scale protein crystals. We are developing new approaches to growing and screening tiny crystals so that we can take full advantage of the available tools.
We are developing new substrates for diffraction and crystallography experiments. We are developing graphene-based structures as low background solutions for the support of crystalline and living samples under a variety of conditions. At left, crystals are shown sealed within a sheet of graphene paper. At right, we see a sheet that covers a TEM grid is transparent to 10 keV electrons.