Macromolecular Design

Modular Design of Pseudo-Symmetric Protein Complexes

Protein-Protein Interface Detection

This module finds target residues in a protein-protein interface.

Pseudo-symmetric Interface Design

This module Selects symmetry-breaking mutations at interfaces.

Design Scoring and Evaluation

This module evaluates designs with different interface residues.

Selection of Designed Sequences

This module finds sequences that meet evaluation criteria.

Immunoglobulin Design